Natural killer cell anergy to cytokine stimulants in a subgroup of patients with heart failure: relationship to norepinephrine.

@article{Vredevoe1995NaturalKC,
  title={Natural killer cell anergy to cytokine stimulants in a subgroup of patients with heart failure: relationship to norepinephrine.},
  author={D. Vredevoe and Debra Kay Moser and Xiaohu Gan and Benjamin Bonavida},
  journal={Neuroimmunomodulation},
  year={1995},
  volume={2 1},
  pages={16-24}
}
Heart failure is a disease characterized by chronically high levels of plasma norepinephrine and anergy in the cytotoxicity of circulating natural killer (NK) lymphocytes. This study shows that NK anergy extends to a significantly reduced cytotoxicity in response to the powerful NK stimulants, interleukin (IL)-2 and interferon (IFN)-alpha. Fifteen patients with heart failure, New York Heart Association stage III or IV, were studied for NK-cell-mediated cytotoxicity. The patients were divided… CONTINUE READING

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…