Natural killer cell activity in fawn-hooded rats

Abstract

Fawn-hooded (FH) rats were shown to lack the genetically conditioned defect of natural killer (NK) activity hypothesized to be present by analogy with the Chediak-Higashi syndrome (CHS) in mice and human beings. In 4-h51Cr release assays, splenic NK cells from FH rats killed YAC-1, RL♂ 1 and G1-TC tumor targets without deficiency based upon comparison with… (More)
DOI: 10.1007/BF01955321

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