Natural killer cell accumulation in tumors is dependent on IFN-gamma and CXCR3 ligands.


Several studies have correlated high numbers of tumor-infiltrating natural killer (NK) cells with a good prognosis for cancer patients. Our study aimed at identifying factors controlling intratumoral NK cell accumulation in s.c. injected NK cell sensitive tumor models and at studying their effect on survival time of recipient mice. We observed that fewer NK… (More)
DOI: 10.1158/0008-5472.CAN-08-1440


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