Natural killer T cells and autoimmune disease.

  title={Natural killer T cells and autoimmune disease.},
  author={Lan Wu and Luc Van Kaer},
  journal={Current molecular medicine},
  volume={9 1},
Natural killer T (NKT) cells are an unusual subset of innate immune cells that express a surface receptor generated by somatic DNA rearrangement, a hallmark of cells of the adaptive immune system. NKT cells express a highly restricted repertoire of T cell receptors that recognize glycolipid antigens bound with the antigen-presenting molecule CD1d. A hallmark of NKT cells is their capacity to produce copious amounts of immunomodulatory cytokines upon antigenic stimulation, which endows these… CONTINUE READING
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