Natural infection of man with group A streptococci. Levels; restriction in class, subclass, and type; and clonal appearance of polysaccharide-group-specific antibodies.


The level of antibodies specific for the two serologically distinct polysaccharides of group A and group A-variant streptococci was investigated in human sera by a modified Farr technique. Whereas there was an obvious relationship between the anti-streptolysin O titer and the level of group-A-specific antibodies, suggesting a recent streptococcal infection… (More)


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