Natural immune boosting in pertussis dynamics and the potential for long-term vaccine failure

@article{Lavine2011NaturalIB,
  title={Natural immune boosting in pertussis dynamics and the potential for long-term vaccine failure},
  author={J. Lavine and A. King and O. Bj{\o}rnstad},
  journal={Proceedings of the National Academy of Sciences},
  year={2011},
  volume={108},
  pages={7259 - 7264}
}
Incidence of whooping cough, unlike many other childhood diseases for which there is an efficacious vaccine, has been increasing over the past twenty years despite high levels of vaccine coverage. Its reemergence has been particularly noticeable among teenagers and adults. Many hypotheses have been put forward to explain these two patterns, but parsimonious reconciliation of clinical data on the limited duration of immunity with both pre- and postvaccine era age-specific incidence remains a… Expand
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