Natural history of pediatric-onset inflammatory bowel disease: a systematic review.

@article{Abraham2012NaturalHO,
  title={Natural history of pediatric-onset inflammatory bowel disease: a systematic review.},
  author={Bincy P. Abraham and Seema A Mehta and Hashem B. El-Serag},
  journal={Journal of clinical gastroenterology},
  year={2012},
  volume={46 7},
  pages={581-9}
}
BACKGROUND/AIMS There has been no systematic review of natural history studies of pediatric-onset inflammatory bowel disease (IBD). We conducted a systematic review focused on understanding the long-term risks of growth failure, disease reclassification and extension, hospitalizations, cancer and death among patients with childhood IBD. METHODS PubMed searches and subsequent data abstraction were performed by 2 independent investigators. Studies published full in english with a 5-year minimum… CONTINUE READING