Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays.

Abstract

Paroxysmal nocturnal haemoglobinuria (PNH) is an uncommon, acquired disorder of blood cells caused by mutation of the phosphatidylinositol glycan class A (PIG-A) gene. The disease often manifests with haemoglobinuria, peripheral blood cytopenias, and venous thrombosis. The natural history of PNH has been documented in retrospective series; but there has… (More)

Topics

Cite this paper

@article{Moyo2004NaturalHO, title={Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays.}, author={Victor M. Moyo and Galina L. Mukhina and Elizabeth S. Garrett and Robert A Brodsky}, journal={British journal of haematology}, year={2004}, volume={126 1}, pages={133-8} }