Natural history of multiple sclerosis

@article{Weinshenker2005NaturalHO,
  title={Natural history of multiple sclerosis},
  author={Brian G. Weinshenker},
  journal={Annals of Neurology},
  year={2005},
  volume={36}
}
Multiple sclerosis (MS) is the most common idiopathic inflammatory disease of the central nervous system. The distinction between MS and other benign or fulminant inflammatory demyelinating disorders is based on quantitative, rather than qualitative, differences in chronicity and severity. Primary progressive MS may differ from relapsing‐remitting MS in MRI lesion frequency, immunogenetic profile, responsiveness to immunosuppressive treatment, and histology. In 60% of patients, MS begins as a… 
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