Natural history of cartilage damage and osteoarthritis progression on magnetic resonance imaging in a population-based cohort with knee pain.

@article{Cibere2011NaturalHO,
  title={Natural history of cartilage damage and osteoarthritis progression on magnetic resonance imaging in a population-based cohort with knee pain.},
  author={Jolanda Cibere and Eric C Sayre and Ali Guermazi and Savvas Nicolaou and Jacek A. Kopec and John M. Esdaile and Anona Thorne and Joel Singer and Hui Sze Wong},
  journal={Osteoarthritis and cartilage},
  year={2011},
  volume={19 6},
  pages={683-8}
}
OBJECTIVES To determine the natural history of cartilage damage and of osteoarthritis (OA) progression using magnetic resonance imaging (MRI); to evaluate whether OA progression varies by stage of disease. METHODS A population-based cohort with knee pain was assessed clinically, with X-ray (Kellgren-Lawrence [KL] grading) and MRI. Cartilage was graded 0-3 on six joint surfaces. Frequency of cartilage damage change was determined for each joint site. Progression of OA was defined as a… CONTINUE READING