Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac disease.

@article{Liu2007NaturalHO,
  title={Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac disease.},
  author={Edwin Liu and Marcella Li and Lisa Emery and Iman Taki and Kathy Barriga and Claudio Tiberti and George S. Eisenbarth and Marian Rewers and Edward J. Hoffenberg},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={2007},
  volume={45 3},
  pages={293-300}
}
INTRODUCTION Gliadin proteins play a key role in the pathogenesis of celiac disease; however, as a screen for celiac disease, anti-gliadin antibody testing has been replaced by the more sensitive and specific serological assays for transglutaminase autoantibodies (TGAA). A new generation of anti-gliadin antibody assays has been developed to detect synthetic, deamidated homologous gliadin peptides (DGP) with high sensitivity and specificity. METHODS Sera were collected prospectively from… CONTINUE READING

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