Natural history and staging of chronic myelogenous leukemia.

@article{Cortes2004NaturalHA,
  title={Natural history and staging of chronic myelogenous leukemia.},
  author={Jorge E. Cortes},
  journal={Hematology/oncology clinics of North America},
  year={2004},
  volume={18 3},
  pages={569-84, viii}
}
  • Jorge E. Cortes
  • Published 2004 in Hematology/oncology clinics of North America
The natural history of chronic myelogenous leukemia (CML) has changed in recent years, partly due to earlier diagnosis but mostly as a consequence of the availability of effective therapies that have the potential to eradicate the Philadelphia chromosome-positive clone. Highly effective therapy with imatinib has changed the prognostic significance of clinical features traditionally associated with poor outcome. Achieving a complete cytogenetic response and a major molecular response early… CONTINUE READING

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