Natural engineering principles of electron tunnelling in biological oxidation–reduction

@article{Page1999NaturalEP,
  title={Natural engineering principles of electron tunnelling in biological oxidation–reduction},
  author={Christopher C. Page and C. Moser and Xiaoxi Chen and P. Dutton},
  journal={Nature},
  year={1999},
  volume={402},
  pages={47-52}
}
We have surveyed proteins with known atomic structure whose function involves electron transfer; in these, electrons can travel up to 14 Å between redox centres through the protein medium. Transfer over longer distances always involves a chain of cofactors. This redox centre proximity alone is sufficient to allow tunnelling of electrons at rates far faster than the substrate redox reactions it supports. Consequently, there has been no necessity for proteins to evolve optimized routes between… Expand
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