Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta.


This study investigated the possible active principles which support the endothelial nitric oxide-dependent relaxation produced by red wine and other plant polyphenolic compounds in thoracic aorta from male Wistar rats (12-14 wk old). Relaxation experiments were recorded isometrically on vessels precontracted with norepinephrine. Ten different… (More)