Natural cytotoxicity of peripheral blood lymphocytes and regional lymph node cells in breast cancer in women.

@article{CunninghamRundles1981NaturalCO,
  title={Natural cytotoxicity of peripheral blood lymphocytes and regional lymph node cells in breast cancer in women.},
  author={Susanna Cunningham-Rundles and Daniel A Filippa and Dr. rer. med. W. Braun and Paolo Antonelli and H Ashikari},
  journal={Journal of the National Cancer Institute},
  year={1981},
  volume={67 3},
  pages={585-90}
}
Natural cytotoxicity was studied before surgery or other treatment in 83 women with primary, untreated breast cancer. Peripheral blood lymphocytes (PBL) and cytotoxicity of regional lymph node cell(s) (RLNC) were examined in a 4-hour 51Cr release assay against the target cell K-562. Results indicated that greater than one-third of breast cancer patients have more negative lymphocyte cytotoxic activity toward K-562 than do the other two-thirds. Similar results were observed for PBL of 25… CONTINUE READING