Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells

@article{Herberman1975NaturalCR,
  title={Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells},
  author={R. Herberman and M. Nunn and H. T. Holden and D. Lavrin},
  journal={International Journal of Cancer},
  year={1975},
  volume={16}
}
  • R. Herberman, M. Nunn, +1 author D. Lavrin
  • Published 1975
  • Biology, Medicine
  • International Journal of Cancer
  • Studies were performed to characterize the effector cells responsible for natural cytotoxicity of mouse lymphoid cells against a variety of syngeneic and allogeneic tumor lines. Since spleen cells from normal nude mice were found to be highly cytotoxic, they were used for most of these experiments. Only a small proportion of the reactivity was affected by treatment with anti‐θ serum plus complement. Macrophages did not appear to be responsible for the reactivity, since treatment with carbonyl… CONTINUE READING
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