Natural cyclopeptaibiotics and related cyclic tetrapeptides: structural diversity and future prospects.

  title={Natural cyclopeptaibiotics and related cyclic tetrapeptides: structural diversity and future prospects.},
  author={Thomas Degenkolb and Walter Gams and H. K. Brueckner},
  journal={Chemistry & biodiversity},
  volume={5 5},
Linearity is not considered a prerequisite anymore, and extension of the current definition of 'peptaibiotics' to cyclic, Aib-containing peptides is proposed. Sequences and bioactivities, together with ecophysiological importance of cyclopeptaibiotics and related cyclic tetrapeptides, and their fungal-taxonomic relationships, are discussed. 

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