Natural course of acute hepatitis C: a long-term prospective study.

  title={Natural course of acute hepatitis C: a long-term prospective study.},
  author={Teresa Santantonio and Emanuele Sinisi and Angela Guastadisegni and Caterina Casalino and Michele Mazzola and Annamaria Gentile and Gioacchino Leandro and Giuseppe Pastore},
  journal={Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver},
  volume={35 2},
BACKGROUND Acute hepatitis C has a high chronicity rate which appears to be significantly reduced by early antiviral treatment. However, it is unclear if all acutely infected patients should be treated, and when. In this prospective study, patients with a well-documented diagnosis of acute hepatitis C were evaluated to define the natural course, the rate of chronicity, and host and virus-related factors which might predict a self-limiting or chronic evolution requiring early antiviral treatment… CONTINUE READING
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