Natural antioxidants and hypertension: promise and challenges.

@article{Kizhakekuttu2010NaturalAA,
  title={Natural antioxidants and hypertension: promise and challenges.},
  author={Tinoy J Kizhakekuttu and Michael E Widlansky},
  journal={Cardiovascular therapeutics},
  year={2010},
  volume={28 4},
  pages={
          e20-32
        }
}
Hypertension reigns as a leading cause of cardiovascular morbidity and mortality worldwide. Excessive reactive oxygen species (ROS) have emerged as a central common pathway by which disparate influences may induce and exacerbate hypertension. Potential sources of excessive ROS in hypertension include nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, mitochondria, xanthine oxidase, endothelium-derived NO synthase, cyclooxygenase 1 and 2, cytochrome P450 epoxygenase, and transition… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 163 references

A placebo-controlled study of the effect of Cardiovascular Therapeutics

Y Hata, M Yamamoto, +3 authors T. Takano
Am J Clin Nutr 1996;64:767–771 • 2010
View 1 Excerpt

A randomised controlled trial

K Ried, OR Frank, prehypertension Stocks NP. Dark chocolate or tomato extract for
BMC Complement Altern Med 2009;9:22–33. e28 Cardiovascular Therapeutics 28 • 2010
View 2 Excerpts

Antioxidants prevent health-promoting effects of physical exercise in humans.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 1 Excerpt

Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension.

American journal of physiology. Regulatory, integrative and comparative physiology • 2009
View 1 Excerpt