Natural and totally synthetic receptors in the innovative design of HPLC chiral stationary phases

@article{Gasparrini2003NaturalAT,
  title={Natural and totally synthetic receptors in the innovative design of HPLC chiral stationary phases},
  author={Francesco Gasparrini and Ilaria D'acquarica and D. Misiti and Marco Pierini and Claudio Villani},
  journal={Pure and Applied Chemistry},
  year={2003},
  volume={75},
  pages={407 - 412}
}
Abstract An overview is presented of the experimental results obtained by our group in the design, realization, and applications of high-performance liquid chromatography (HPLC) enantioselective stationary phases based on surface-linked macrocyclic receptors. Macrocyclic synthetic receptors and macrocyclic glycopeptide receptors have been grafted on silica particles, and the resulting chiral stationary phases are used to monitor differential associations of the enantiomers of selected chiral… 
View via Publisher
iupac.org
13 Citations
Highly Influential Citations
1
Background Citations
3
Methods Citations
1

Figures from this paper

13 Citations

Twenty years of research on silica-based chiral stationary phases.
TLDR
An overview of twenty years of pioneering work (from 1985 to 2005) of the research group in the preparation and application of enantioselective packing materials for HPLC is provided.
Retention mechanism of high-performance liquid chromatographic enantioseparation on macrocyclic glycopeptide-based chiral stationary phases.
Enantioseparations by high-performance liquid chromatography using macrocyclic glycopeptide-based chiral stationary phases: an overview.
TLDR
This overview chapter provides a brief summary of general aspects of macrocyclic antibiotic-based chiral stationary phases including their preparation and their application to direct enantioseparations of various racemates focusing on the literature published since 2004.
High-Performance Liquid Chromatography Enantioseparations Using Macrocyclic Glycopeptide-Based Chiral Stationary Phases: An Overview.
TLDR
This overview chapter provides a brief summary of general aspects of antibiotic-based chiral stationary phases including their preparation and their application to direct enantioseparations of various racemates focusing on the literature published since 2004.
9.06 The Use of Preparative Chiral Chromatography for Accessing Enantiopurity in Pharmaceutical Discovery and Development
Chiral separations
  • K. Phinney
  • Chemistry, Biology
    Methods in Molecular Biology
  • 2019
TLDR
This introductory chapter briefly summarizes the present understanding of the structural enantioselective recognition processes for various types of chiral selectors.
Macrocyclic Antibiotic Selectors in Direct HPLC Enantioseparations
In the past few decades, macrocyclic antibiotic molecules have become among the most useful chiral selectors in analytical HPLC, thin-layer chromatography and capillary electrophoresis and also in…
Enantio- and chemo-selective HPLC separations by chiral-achiral tandem-columns approach: the combination of CHIROBIOTIC TAG and SCX columns for the analysis of propionyl carnitine and related impurities.
Enantiomeric separation of nonproteinogenic amino acids by high-performance liquid chromatography.
The market of chiral drugs: Chiral switches versus de novo enantiomerically pure compounds
...
...

References

SHOWING 1-10 OF 16 REFERENCES
Chiral separations : applications and technology
TLDR
Chiral Separation Methods Development of Chiral Methods Stereoselective Renal Elimination of Drugs Stereochemical Analyses of Food Components Chromatography as a Separation Tool for the Preparative Resolution of Racemic Compounds Enantioselectives Transport Through Liquid Membranes.
Pure and Applied Chemistry
Synthesis of a novel brominated vinylic fatty acid antileishmanial activity effectively inhibits the Leishmania topoisomerase IB enzyme by halogen bond formation
Tetrahedron: Asymmetry
  • 2005
Chiral Separations: Applications and Technology, American Chemical Society, Washington, DC
  • 1997
J. Chromatogr. A
  • J. Chromatogr. A
  • 1999
J. Chromatogr. A
  • J. Chromatogr. A
  • 2001
C. Still. J. Org. Chem
  • C. Still. J. Org. Chem
  • 1995
Anal. Chem
  • Anal. Chem
  • 2000
Org. Lett
  • Org. Lett
  • 2002
J. Chromatogr. A
  • J. Chromatogr. A
  • 1996
...
...