Natural and synthetic betaines counter the effects of high NaCl and urea concentrations.

  title={Natural and synthetic betaines counter the effects of high NaCl and urea concentrations.},
  author={K. Randall and M. Lever and B. Peddie and S. Chambers},
  journal={Biochimica et biophysica acta},
  volume={1291 3},
  • K. Randall, M. Lever, +1 author S. Chambers
  • Published 1996
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • Escherichia coli was used as a model system to evaluate a range of betaines for their ability to protect against salt and urea stresses. Betaine structure determined the salt and urea protective effects. Dimethylthetin conferred salt protection similar to glycine betaine, whereas dimethylsulfoniopropionate (DMSP) was less effective than either glycine betaine or dimethylthetin, but similar to propionobetaine (its nitrogen analogue). Hydrophobic alpha-substituents altered salt tolerance. Valine… CONTINUE READING
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