Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.

Abstract

Mouse natural killer T (NKT) cells expressing an invariant T cell antigen receptor (TCR) recognize glycosphingolipids (GSLs) from Sphingomonas bacteria. The synthetic antigens previously tested, however, were designed to closely resemble the potent synthetic agonist alpha-galactosyl ceramide (alphaGalCer), which contains a monosaccharide and a C18:0… (More)
DOI: 10.1016/j.chembiol.2008.05.012

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Cite this paper

@article{Kinjo2008NaturalSG, title={Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.}, author={Yuki Kinjo and Bo Pei and Simone Bufali and Ravinder Raju and Stewart K. Richardson and Masakazu Imamura and Masakazu Fujio and Douglass Wu and Archana Khurana and Kazuyoshi Kawahara and Chi-Huey Wong and Amy R Howell and Peter H Seeberger and Mitchell Kronenberg}, journal={Chemistry & biology}, year={2008}, volume={15 7}, pages={654-64} }