Natural Selection Affects Multiple Aspects of Genetic Variation at Putatively Neutral Sites across the Human Genome


A major question in evolutionary biology is how natural selection has shaped patterns of genetic variation across the human genome. Previous work has documented a reduction in genetic diversity in regions of the genome with low recombination rates. However, it is unclear whether other summaries of genetic variation, like allele frequencies, are also… (More)
DOI: 10.1371/journal.pgen.1002326


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