Natural Schistosoma mansoni infection in Nectomys squamipes: histopathological and morphometric analysis in comparison to experimentally infected N. squamipes and C3H/He mice.

@article{CostaSilva2002NaturalSM,
  title={Natural Schistosoma mansoni infection in Nectomys squamipes: histopathological and morphometric analysis in comparison to experimentally infected N. squamipes and C3H/He mice.},
  author={Michele Costa-Silva and Ros{\~a}ngela Rodrigues-Silva and Maarten Hulstijn and Renata Heisler Neves and M{\^o}nica de Souza Panasco and Henrique Leonel Lenzi and Jos{\'e} Roberto Machado-Silva},
  journal={Memorias do Instituto Oswaldo Cruz},
  year={2002},
  volume={97 Suppl 1},
  pages={
          129-42
        }
}
Histopathologic and morphometric (area, perimeter, major and minor diameters) analysis of hepatic granulomas isolated from twelve naturally infected Nectomys squamipes were compared to four experimentally infected ones and six C3H/He mice. Liver paraffin sections were stained for cells and extracellular matrix. Both groups of N. squamipes presented peculiar granulomas consisting predominantly of large macrophages, full of schistosome pigment, characterizing an exudative-macrophage granuloma… CONTINUE READING

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