Natural History Of Hemophilic Joint Disease Using Sensitive Imaging With Magnetic Resonance Imaging (MRI)

@article{Glorioso2013NaturalHO,
  title={Natural History Of Hemophilic Joint Disease Using Sensitive Imaging With Magnetic Resonance Imaging (MRI)},
  author={T. Glorioso and J. Kittelson and M. Manco-Johnson and B. Lundin and W. Hong and J. Oldenburg and T. Blades},
  journal={Blood},
  year={2013},
  volume={122},
  pages={209-209}
}
![Graphic][1] Introduction Arthropathy, the most costly chronic complication of severe hemophilia A (HemA) can be prevented by routine replacement of factor VIII (FVIII) when initiated prior to joint bleeding (primary prophylaxis) [ NEJM ;357:535]. However, the efficacy of prophylaxis initiated after the onset of recurrent hemarthroses or with established arthropathy (secondary or tertiary prophylaxis) is unknown. This individual patient meta-analysis was performed to derive the natural… Expand
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Outcome measures in Haemophilia: Beyond ABR (Annualized Bleeding Rate)