Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles

@article{Kiss2011NaturalAH,
  title={Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles},
  author={Elina A. Kiss and C. Vonarbourg and Stefanie Kopfmann and E. Hobeika and D. Finke and C. Esser and A. Diefenbach},
  journal={Science},
  year={2011},
  volume={334},
  pages={1561 - 1565}
}
  • Elina A. Kiss, C. Vonarbourg, +4 authors A. Diefenbach
  • Published 2011
  • Biology, Medicine
  • Science
    • Nutrients can shape immune system development function through aryl hydrocarbon receptor signaling. Innate lymphoid cells (ILC) expressing the transcription factor RORγt induce the postnatal formation of intestinal lymphoid follicles and regulate intestinal homeostasis. RORγt+ ILC express the aryl hydrocarbon receptor (AhR), a highly conserved, ligand-inducible transcription factor believed to control adaptation of multicellular organisms to environmental challenges. We show that AhR is… CONTINUE READING
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    Paper Mentions

    Interventional Clinical Trial
    The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor Activation
    This study evaluates the role of dietary L-tryptophan, an essential amino acid, in the activation of a specific cellular component: the aryl hydrocarbon receptor.  
    ConditionsDiet Modification
    InterventionDietary Supplement
    McMaster University
    November 2017 - June 2018
    Blog Post
    You AhR What You Eat: Linking Diet and Immunity.
    Nutri-Link Ltd - Clinical Education
    29 November 2011
    571 Citations
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