Natriuretic peptides in chronic kidney disease and during renal replacement therapy: an update.

@article{Khalifeh2009NatriureticPI,
  title={Natriuretic peptides in chronic kidney disease and during renal replacement therapy: an update.},
  author={Neda Khalifeh and Dominik Georg Haider and Walter Hermann H{\"o}rl},
  journal={Journal of investigative medicine : the official publication of the American Federation for Clinical Research},
  year={2009},
  volume={57 1},
  pages={33-9}
}
Natriuretic peptides play a major role in sodium and body volume homeostasis in patients with adequate kidney function. Circulating B-type natriuretic peptide (BNP) and its amino-terminal fragment NT-proBNP provide important information on cardiac dysfunction, hypervolemia, and risk for hospitalization or death even in patients with severe impairment of kidney function. NT-proBNP acts also as significant independent predictor of progression of chronic kidney disease (CKD). Differences in… CONTINUE READING