Natriuretic peptides, respiratory disease, and the right heart.

  title={Natriuretic peptides, respiratory disease, and the right heart.},
  author={Lok Bin Yap and Dev Mukerjee and Peter Mclean Timms and Houman Ashrafian and John Gerard Coghlan},
  volume={126 4},
It is well-recognized that atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are raised in conditions with ventricular volume and pressure overload. In addition to this established role in left ventricular congestive cardiac failure, there is good evidence that BNP has a diagnostic role in right ventricular (RV) dysfunction and pulmonary arterial hypertension (PAH). For example, BNP levels can be used to differentiate between dyspneic patients with pure respiratory defects… CONTINUE READING