Natriuretic Peptide Receptor-C is Up-Regulated in the Intima of Advanced Carotid Artery Atherosclerosis.

@article{Zayed2016NatriureticPR,
  title={Natriuretic Peptide Receptor-C is Up-Regulated in the Intima of Advanced Carotid Artery Atherosclerosis.},
  author={Mohamed Ahmed Zayed and Scott D Harring and Dana Abendschein and Chandu Vemuri and Danielle W. Lu and Lisa Detering and Yongjian Liu and Pamela K. Woodard},
  journal={Journal of medical & surgical pathology},
  year={2016},
  volume={1 3}
}
OBJECTIVE Natriuretic peptide receptor-C (NPR-C/NPR-3) is a cell surface protein involved in vascular remodelling that is up-regulated in atherosclerosis. NPR-C expression has not been well characterized in human carotid artery occlusive lesions. We hypothesized that NPR-C expression correlates with intimal features of vulnerable atherosclerotic carotid artery plaque. METHODS To test this hypothesis, we evaluated NPR-C expression by immunohistochemistry (IHC) in carotid endarterectomy (CEA… CONTINUE READING

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