Native ion current coupled to purinergic activation via basal and mechanically induced ATP release in Xenopus follicles.

@article{Saldaa2009NativeIC,
  title={Native ion current coupled to purinergic activation via basal and mechanically induced ATP release in Xenopus follicles.},
  author={Carlos Salda{\~n}a and Edith Garay and Gisela Edith Rangel and Luis Manuel Reyes and Rogelio O Arellano},
  journal={Journal of cellular physiology},
  year={2009},
  volume={218 2},
  pages={355-65}
}
Xenopus follicle-enclosed oocytes are endowed with purinergic receptors located in the follicular cell membrane; their stimulation by ATP elicits an electrical response that includes generation of a fast inward current (F(Cl)) carried by Cl(-). Here, it was found that mechanical stimulation of the follicle provoked a native electrical response named I(mec). This was dependent on coupling between oocyte and follicular cells, because I(mec) was eliminated by enzymatic defolliculation or… CONTINUE READING