National trends in Fontan operation and in-hospital outcomes in the USA

  title={National trends in Fontan operation and in-hospital outcomes in the USA},
  author={Emmanuel Akintoye and William R. Miranda and Gruschen R. Veldtman and Heidi M Connolly and Alexander C. Egbe},
  pages={708 - 714}
Background National prevalence and outcomes of Fontan operation in the USA is unknown. Study objective was to determine trends (temporal change) in the annual volume of Fontan operations, in-hospital mortality, postoperative complications and type of hospital discharge. Methods Review of the Nationwide Inpatient Sample for patients that underwent Fontan operation from 2001 to 2014 using the International Classification of Diseases-Ninth Revision, Clinical Modification procedure code for Fontan… 
The Epidemiology of Persons Living with Fontan in 2020 and Projections for 2030: Development of an Epidemiology Model Providing Multinational Estimates
The epidemiology of persons living with Fontan was modelled by applying these surgery frequencies to mid-year populations from 1972 to 2020 and overlaying an uptake curve, and according to this epidemiology model, the Fontan population is growing, partly driven by increased survival rates with the more recent LT-TCPC and EC- TCPC procedures (compared with AP).
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The miniaturized Fontan circulation assist device (mini-FCAD) was successfully tested in vivo as a right heart replacement device demonstrating adequate circulatory support and normal physiologic pulmonary and venous pressures.
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In perioperative survivors of Fontan surgery, gradual attrition occurs predominantly from thromboembolic, heart failure–related, and sudden deaths.
The extracardiac conduit Fontan procedure in Australia and New Zealand: hypoplastic left heart syndrome predicts worse early and late outcomes.
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The extracardiac Fontan procedure provides excellent survival into the second decade of life, but half of patients will suffer a late adverse event by 14 years, and patients with HLHS are at higher risk of late adverse events than other morphological groups, but their survival is still excellent.
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Liver health in adults with Fontan circulation: A multicenter cross‐sectional study