Natalizumab use in pediatric multiple sclerosis.

Abstract

BACKGROUND Natalizumab, a humanized monoclonal antibody raised against alpha4 integrins, is approved for treatment of active relapsing-remitting multiple sclerosis (RRMS) in adult patients. OBJECTIVE To determine the safety, effectiveness, and tolerability of natalizumab use in pediatric patients with MS. DESIGN Case report. SETTING Center for MS in… (More)
DOI: 10.1001/archneur.65.12.1655

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