Nasopharyngeal colonization with nontypeable Haemophilus influenzae and recurrent otitis media. Tonawanda/Williamsville Pediatrics.

@article{Harabuchi1994NasopharyngealCW,
  title={Nasopharyngeal colonization with nontypeable Haemophilus influenzae and recurrent otitis media. Tonawanda/Williamsville Pediatrics.},
  author={Yasuaki Harabuchi and Howard Faden and Noboru Yamanaka and Lynn Duffy and Judy Wolf and Deborah A Krystofik},
  journal={The Journal of infectious diseases},
  year={1994},
  volume={170 4},
  pages={862-6}
}
The relationship between nasopharyngeal colonization with nontypeable H. influenzae and recurrent otitis media was assessed in 157 children followed prospectively from birth through 12 months of age. Forty-nine (31%) became colonized. Nasopharyngeal secretory IgA (sIgA) reactive with the P6 outer membrane protein was detected in all colonized children. Reduction or elimination of the organism was associated with a better mucosal immune response (560 +/- 864 units/ng/mL of sIgA) than was… CONTINUE READING

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