Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

@inproceedings{Menet2012NascentSeqRN,
  title={Nascent-Seq reveals novel features of mouse circadian transcriptional regulation},
  author={Jerome S Menet and Joseph M. Tortes i Rodriguez and Katharine C Abruzzi and Michael Rosbash},
  booktitle={eLife},
  year={2012}
}
A substantial fraction of the metazoan transcriptome undergoes circadian oscillations in many cells and tissues. Based on the transcription feedback loops important for circadian timekeeping, it is commonly assumed that this mRNA cycling reflects widespread transcriptional regulation. To address this issue, we directly measured the circadian dynamics of… CONTINUE READING