Nasal ventilation alters mesenchymal cell turnover and improves alveolarization in preterm lambs.

@article{Reyburn2008NasalVA,
  title={Nasal ventilation alters mesenchymal cell turnover and improves alveolarization in preterm lambs.},
  author={Brent Reyburn and Marlana Li and Drew B Metcalfe and Nicholas J Kroll and Jeremy Alvord and Albert Wint and Mar Janna Dahl and Jiancheng Sun and Li Dong and Zheng-ming Wang and Christopher W. Callaway and Robert A McKnight and Laurie J. Moyer-Mileur and Bradley A. Yoder and Donald M. Null and Robert H. S. Lane and Kurt H. Albertine},
  journal={American journal of respiratory and critical care medicine},
  year={2008},
  volume={178 4},
  pages={407-18}
}
RATIONALE Bronchopulmonary dysplasia (BPD) is a frequent cause of morbidity in preterm infants that is characterized by prolonged need for ventilatory support in an intensive care environment. BPD is characterized histopathologically by persistently thick, cellular distal airspace walls. In normally developing lungs, by comparison, remodeling of the immature parenchymal architecture is characterized by thinning of the future alveolar walls, a process predicated on cell loss through apoptosis… CONTINUE READING

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