Nasal pepsin assay and pH monitoring in chronic rhinosinusitis.

  title={Nasal pepsin assay and pH monitoring in chronic rhinosinusitis.},
  author={S{\"u}ay Ozmen and Omer Taşkin Y{\"u}cel and Incilkay Sinici and Omer Afşın Ozmen and Ahmet Emre S{\"u}sl{\"u} and Oğuz Oğretmenoğlu and Metin Onerci},
  journal={The Laryngoscope},
  volume={118 5},
OBJECTIVES/HYPOTHESIS The primary objective of this study was to determine the relationship between chronic rhinosinusitis (CRS) and laryngopharyngeal reflux (LPR). We also investigated the diagnostic value of pepsin in nasal lavage by means of fluorometric assay as compared with 24-hour dual-probe pH monitoring. STUDY DESIGN AND METHODS This is a controlled, prospective study from a retrospective dataset of 33 patients recruited for endoscopic sinus surgery between 2005 and 2006 in a… CONTINUE READING


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