Nasal inflammation and bronchial reactivity to methacholine in atopic children with respiratory symptoms.

@article{Sale2003NasalIA,
  title={Nasal inflammation and bronchial reactivity to methacholine in atopic children with respiratory symptoms.},
  author={Rosa Sale and Michela Silvestri and Elena Battistini and A. C. Defilippi and Federica Sabatini and Silvia Pecora and Giovanni A Rossi},
  journal={Allergy},
  year={2003},
  volume={58 11},
  pages={1171-5}
}
BACKGROUND In atopic subjects, dysfunctions of the upper and lower airways frequently coexist and allergic rhinitis seems to constitute a risk factor for the occurrence of asthma in predisposed individuals. AIM OF THE STUDY To evaluate whether in atopic subjects nasal inflammation could reflect changes in respiratory functions, 11 allergic children, sensitized to house dust mites (HDM), with rhinoconjunctivitis and asthma and 10 nonatopic controls (ctrs) were studied. METHODS All subjects… CONTINUE READING