Nasal health in Down syndrome: A cross-sectional study

@article{Chen2006NasalHI,
  title={Nasal health in Down syndrome: A cross-sectional study},
  author={Margaret A. Chen and Timothy Lander and Claire Murphy},
  journal={Otolaryngology–Head and Neck Surgery},
  year={2006},
  volume={134},
  pages={741 - 745}
}

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References

SHOWING 1-10 OF 21 REFERENCES
Prevalence of olfactory impairment in older adults.
TLDR
It is demonstrated that prevalence of olfactory impairment among older adults is high and increases with age, and self-report significantly underestimated prevalence rates obtained by olfaction testing.
Olfactory function in young adolescents with Down's syndrome.
TLDR
Tests of odour discrimination and identification suggest that Down's syndrome related olfactory dysfunction occurs only at ages when Alzheimer's disease-like pathology is present, and that these findings, along with those from studies of Olfactory function in older patients with Down’s syndrome, suggest that this issue isomersally related.
Olfactory dysfunction in down's syndrome
Otolaryngologic manifestations of Down syndrome.
Efficacy of adenoidectomy in the treatment of nasal and middle ear symptoms in children with Down syndrome.
Olfactory Deficits in down Subjects: A Link with Alzheimer Disease
TLDR
Considering the similarity between the neurodegenerative brain pathology exhibited by Alzheimer patients and Down subjects and a recent observation that the former show pathological changes also in the olfactory epithelium (neuritic plaques and neurofibrillary tangles), these two Olfactory tasks could represent a useful noninvasive diagnostic method.
Cilia ultrastructure in children with Down syndrome.
TLDR
This study is the first to be carried out to determine if cilia ultrastructure abnormalities are prevalent in the population with Down syndrome, and four of 10 patients had documented cilia abnormalities, but these were present in the background of normal cilia, suggesting that they were the result rather than the cause of chronic sinusitis.
...
1
2
3
...