Nasal health in Down syndrome: A cross-sectional study
@article{Chen2006NasalHI, title={Nasal health in Down syndrome: A cross-sectional study}, author={Margaret A. Chen and Timothy Lander and Claire Murphy}, journal={Otolaryngology–Head and Neck Surgery}, year={2006}, volume={134}, pages={741 - 745} }
13 Citations
Olfaction in People with Down Syndrome: A Comprehensive Assessment across Four Decades of Age
- Psychology, MedicinePloS one
- 2016
Olfactory function is overall severely impaired in DS people and may be globally impaired at relatively young age, despite of reportedly normal smell.
Ageing and Olfactory Dysfunction in Trisomy 21: A Systematic Review
- Psychology, BiologyBrain sciences
- 2021
Olfactory dysfunction in an individual with trisomy 21 commences at a relatively young age and affects the three olfactory domains, threshold, discrimination, and identification, which are suggested to be impaired in trisome 21 participants with age > 30 years old.
Development of Down Syndrome Research Over the Last Decades–What Healthcare and Education Professionals Need to Know
- MedicineFrontiers in Psychiatry
- 2021
This mini-review provides a concise update on existent information about the heterogeneity of DS from a full-spectrum developmental perspective, within an interdisciplinary context to enable professionals to enhance the quality of prenatal counseling and help parents to set targeted early interventions.
Health of Children 3 to 17 Years of Age With Down Syndrome in the 1997–2005 National Health Interview Survey
- Medicine, PsychologyPediatrics
- 2009
OBJECTIVE. This study provides population-based estimates of recent medical conditions, concurrent developmental disorders, and health impact and utilization indicators for US children with and…
The olfactory system and its disorders.
- MedicineSeminars in neurology
- 2009
The anatomy and physiology of this primary sensory system are reviewed, means of assessing its function, and major diseases and disorders with which it is intimately associated are reviewed.
Intellectual Disability and Ill Health: Systems disorders
- Medicine
- 2010
What do you do to start reading intellectual disability and ill health? Searching the book that you love to read first or find an interesting book that will make you want to read? Everybody has…
An age-related axon terminal pathology around the first olfactory relay that involves amyloidogenic protein overexpression without plaque formation
- BiologyNeuroscience
- 2012
Analysis of Adult Cerebral Cortex and Hippocampus Transcriptomes Reveals Unique Molecular Changes in the Ts1Cje Mouse Model of Down Syndrome
- BiologyBrain pathology
- 2015
Functional analyses in Ts1Cje mice highlighted the importance of NFAT signaling, oxidative stress, neuroinflammation and olfactory perception via G‐protein signaling and physiologically relevant pathways that can serve as targets for the development of future treatments to improve neurocognition in Down syndrome.
References
SHOWING 1-10 OF 21 REFERENCES
Individuals with Down's syndrome demonstrate abnormal olfactory event-related potentials
- Medicine, PsychologyClinical Neurophysiology
- 1999
Prevalence of olfactory impairment in older adults.
- Psychology, MedicineJAMA
- 2002
It is demonstrated that prevalence of olfactory impairment among older adults is high and increases with age, and self-report significantly underestimated prevalence rates obtained by olfaction testing.
Olfactory function in young adolescents with Down's syndrome.
- Psychology, MedicineJournal of neurology, neurosurgery, and psychiatry
- 1996
Tests of odour discrimination and identification suggest that Down's syndrome related olfactory dysfunction occurs only at ages when Alzheimer's disease-like pathology is present, and that these findings, along with those from studies of Olfactory function in older patients with Down’s syndrome, suggest that this issue isomersally related.
Olfactory impairment increases as a function of age in persons with Down syndrome
- Psychology, MedicineNeurobiology of Aging
- 2002
Otolaryngologic manifestations of Down syndrome.
- MedicineOtolaryngologic clinics of North America
- 2000
Efficacy of adenoidectomy in the treatment of nasal and middle ear symptoms in children with Down syndrome.
- MedicineInternational journal of pediatric otorhinolaryngology
- 2004
Olfactory identification deficits in down's syndrome and idiopathic mental retardation
- PsychologyNeuropsychologia
- 1993
Olfactory Deficits in down Subjects: A Link with Alzheimer Disease
- Psychology, BiologyPerceptual and motor skills
- 1994
Considering the similarity between the neurodegenerative brain pathology exhibited by Alzheimer patients and Down subjects and a recent observation that the former show pathological changes also in the olfactory epithelium (neuritic plaques and neurofibrillary tangles), these two Olfactory tasks could represent a useful noninvasive diagnostic method.
Cilia ultrastructure in children with Down syndrome.
- MedicineThe Journal of otolaryngology
- 2003
This study is the first to be carried out to determine if cilia ultrastructure abnormalities are prevalent in the population with Down syndrome, and four of 10 patients had documented cilia abnormalities, but these were present in the background of normal cilia, suggesting that they were the result rather than the cause of chronic sinusitis.