Nasal eosinophilia: an indicator of eosinophilic inflammation in asthma
@article{Amorim2010NasalEA,
title={Nasal eosinophilia: an indicator of eosinophilic inflammation in asthma},
author={Mm Amorim and A. Araruna and Lilian Serrasqueiro Ballini Caetano and Ana Clara Sousa Cruz and Llka Lopes Santoro and Ana Luisa Godoy Fernandes},
journal={Clinical \& Experimental Allergy},
year={2010},
volume={40}
}Background It is noteworthy that there is a clear clinical, epidemiological and pathophysiological association between upper and lower airway inflammation in rhinitis and asthma.
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References
SHOWING 1-10 OF 37 REFERENCES
Inflammatory subtypes in asthma: Assessment and identification using induced sputum
- Medicine, BiologyRespirology
- 2006
Objective: The authors sought to investigate the detection of non‐eosinophilic asthma using induced sputum. Although this is an important subtype of clinical asthma, its recognition is not…
Nasal Eosinophils Display the Best Correlation with Symptoms, Pulmonary Function and Inflammation in Allergic Rhinitis
- MedicineInternational Archives of Allergy and Immunology
- 2005
Eosinophils in the nasal smear display the best correlation with all the clinical and immunological parameters in allergic rhinitis and also correlate well with methacholine response.
Association between asthma and rhinitis according to atopic sensitization in a population-based study.
- MedicineThe Journal of allergy and clinical immunology
- 2004
Eosinophilic inflammation in sputum of poorly controlled asthmatics
- Medicine, BiologyEuropean Respiratory Journal
- 2002
Sputum eosinophils, LTE4, ECP and RANTES levels (but not IL-8) were significantly higher in patients with poorly controlled asthma as compared to patients with controlled asthma, andsputum cells and sputum inflammatory markers were not different among groups of patients with different severity of asthma.
Asthma and natural colds. Inflammatory indices in induced sputum: a feasibility study.
- Medicine, BiologyAmerican journal of respiratory and critical care medicine
- 1998
It is concluded that induced sputum examination can be used to study the effects of natural colds and influenza on the airways of the lungs and the results suggest that naturalcolds, on Day 4, cause neutrophilic lower airway inflammation that is greater in asthmatics than in healthy subjects.
Comparison between nasal and bronchial inflammation in asthmatic and control subjects.
- MedicineAmerican journal of respiratory and critical care medicine
- 1999
The extent of eosinophilic inflammation of reticular basement membrane thickness and of the epithelium shedding is greater in bronchial than in nasal mucosa of asthmatic patients with perennial rhinitis.
Inflammatory mediators in nasal lavage, induced sputum and serum of employees with rheumatic and respiratory disorders.
- MedicineThe European respiratory journal
- 2001
The data suggest that mediators in nasal lavage samples reflect the occupational exposure to moulds, whereas possible indicators of existing disorders are detectable in serum.
Epithelial shedding is associated with nasal reactions to cold, dry air.
- Medicine, BiologyThe Journal of allergy and clinical immunology
- 2006
Consensus statement * on the treatment of allergic rhinitis
- MedicineAllergy
- 2000
Current guidelines emphasize the importance of an accurate diagnosis of patients presenting with rhinitis symptoms and the morbidity of SAR obviously depends on the geographic region, the pollen season of the plants, and the local climate.