Nasal drug delivery--possibilities, problems and solutions.

  title={Nasal drug delivery--possibilities, problems and solutions.},
  author={Lisbeth Illum},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  volume={87 1-3},
  • Lisbeth Illum
  • Published 2003 in
    Journal of controlled release : official journal…
This paper discusses the problems associated with nasal drug delivery and how it is possible, sometimes by means of quite simple concepts, to improve transport across the nasal membrane. In this way it is feasible to deliver efficiently challenging drugs such as small polar molecules, peptides and proteins and even the large proteins and polysaccharides used in vaccines or DNA plasmids exploited for DNA vaccines. The transport of drugs from the nasal cavity directly to the brain is also… CONTINUE READING
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