Nasal bone assessment in fetuses with trisomy 21 at 16–24 weeks of gestation by three‐dimensional ultrasound

@article{Persico2012NasalBA,
  title={Nasal bone assessment in fetuses with trisomy 21 at 16–24 weeks of gestation by three‐dimensional ultrasound},
  author={Nicola Persico and Francisca Sonia Molina and Guillermo Azumendi and Luigi Fedele and Kypros H. Nicolaides},
  journal={Prenatal Diagnosis},
  year={2012},
  volume={32}
}
OBJECTIVE This study aims to investigate the length and shape of the nasal bones in fetuses with trisomy 21 at 16-24 weeks' gestation. [] Key MethodMETHOD We acquired three-dimensional volumes of the fetal profile from 41 fetuses with trisomy 21. The multiplanar mode was used to measure nasal bone length in the exact midsagittal plane and in parasagittal and oblique views of the fetal face and to examine the nasal bones in the coronal plane.
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18 Citations

Sphenofrontal distance on three‐dimensional ultrasound in euploid and trisomy‐21 fetuses at 16–24 weeks' gestation

  • G. CosselluN. Persico K. Nicolaides
  • Medicine
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • 2016
To compare the distance between the sphenoid and frontal bones on three‐dimensional ultrasound in euploid and trisomy‐21 fetuses at 16–24 weeks' gestation, 3D ultrasound is used for the first time.

Nasal bone length: prenasal thickness ratio: a strong 2D ultrasound marker for Down syndrome

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  • S. KavakE. Kavak
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    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • 2019
This study aimed to compare nasal bone length measurements taken in 2 different planes and to determine whether there is consistency between the measurements.

Spheno‐frontal distance in euploid and trisomy 21 fetuses at 16–24 weeks’ gestation by three‐dimensional ultrasound

A reduction in the growth of the anterior cranial base contributes to the mid-facial hypoplasia observed in fetuses with trisomy 21 and euploid fetuses at 16-24 weeks’ gestation by three-dimensional ultrasound.

Is 3D technique superior to 2D in Down syndrome screening? Evaluation of six second and third trimester fetal profile markers

3D multiplanar correction prior to the measurement of Down syndrome facial markers is superior to subjective judgment of a correct midsagittal plane by 2D technique in second trimester ultrasound investigations.

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Comparison of normal ranges of ultrasonographically measured fetal nasal bone length in the second trimester between different ethnic groups shows that distinct ethnic nomograms should be used in a given population rather than an international model.

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NBL, PT, FP line, PT-NBL ratio and PFSR can be confidently used as DS markers in second trimester ultrasound examinations performed by 2D US.

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