Nasal T-cell lymphoma causally associated with Epstein-Barr virus: clinicopathologic, phenotypic, and genotypic studies.

@article{Harabuchi1996NasalTL,
  title={Nasal T-cell lymphoma causally associated with Epstein-Barr virus: clinicopathologic, phenotypic, and genotypic studies.},
  author={Yasuaki Harabuchi and Shosuke Imai and J Wakashima and Mitsuaki Hirao and Akikatsu Kataura and Toyoro Osato and Shin-ichiro Kon},
  journal={Cancer},
  year={1996},
  volume={77 10},
  pages={2137-49}
}
BACKGROUND The authors have previously demonstrated nasal T-cell lymphoma (NTL) associated with Epstein-Barr virus (EBV). The detailed clinical, phenotypic, and genotypic features and the role of EBV in lymphomagenesis remain to be clarified. METHODS The study group consisted of 18 patients with NTL. The phenotype was determined by immunoperoxidase staining with various monoclonal antibodies. Genotypic study was done using Southern blot hybridization. The presence of EBV-encoded small nuclear… CONTINUE READING
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