Narrow escape problem in two-shell spherical domains.

@article{Mangeat2021NarrowEP,
  title={Narrow escape problem in two-shell spherical domains.},
  author={Matthieu Mangeat and Heiko Rieger},
  journal={Physical review. E},
  year={2021},
  volume={104 4-1},
  pages={
          044124
        }
}
Intracellular transport in living cells is often spatially inhomogeneous with an accelerated effective diffusion close to the cell membrane and a ballistic motion away from the centrosome due to active transport along actin filaments and microtubules, respectively. Recently it was reported that the mean first passage time (MFPT) for transport to a specific area on the cell membrane is minimal for an optimal actin cortex width. In this paper, we ask whether this optimization in a two-compartment… 

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