Narrative review: statin-related myopathy.

@article{Joy2009NarrativeRS,
  title={Narrative review: statin-related myopathy.},
  author={T Sheela Retna Joy and Robert A Hegele},
  journal={Annals of internal medicine},
  year={2009},
  volume={150 12},
  pages={
          858-68
        }
}
Key Summary Points Statin-related myopathy comprises myalgias, myositis, and rhabdomyolysis. Myalgias can affect up to 10% of persons prescribed statins, whereas rhabdomyolysis is rare. The mechanisms responsible for statin-related myopathy are unclear but may include decreased levels of coenzyme Q10, decreased bioavailability of isoprenoids, or mitochondrial dysfunction. Risk factors for myopathy include history of myopathy while receiving another lipid-lowering agent, family history of statin… CONTINUE READING
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