Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet.

@article{Pu2012NaringinAM,
  title={Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet.},
  author={Peng Pu and Dong-mei Gao and Salim Si Mohamed and Jing Chen and Jing Zhang and Xiao-ya Zhou and Nai-Jing Zhou and Jing Xie and Hong Jiang},
  journal={Archives of biochemistry and biophysics},
  year={2012},
  volume={518 1},
  pages={61-70}
}
Metabolic syndrome is a low-grade inflammatory state in which oxidative stress is involved. Naringin, isolated from the Citrussinensis, is a phenolic compound with anti-oxidative and anti-inflammatory activities. The aim of this study was to explore the effects of naringin on metabolic syndrome in mice. The animal models, induced by high-fat diet in C57BL/6 mice, developed obesity, dyslipidemia, fatty liver, liver dysfunction and insulin resistance. These changes were attenuated by naringin… CONTINUE READING

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