Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice

@article{Yang2018NaringinDA,
  title={Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice},
  author={Wenjuan Yang and Keyan Zhou and Yue Zhou and Yuqian An and Tingting Hu and Jing Lu and Shichao Huang and G. Pei},
  journal={Frontiers in Aging Neuroscience},
  year={2018},
  volume={10}
}
Alzheimer’s disease (AD) is a multi-factorial neurodegenerative disorder with abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation and impaired neurogenesis. Mounting evidences suggest that single-target drugs have limited effects on clinical treatment and alternative or multiple targets are required. In recent decades, natural compounds and their derivatives have gained increasing attention in AD drug discovery due to their inherently enormous chemical and structural diversity… Expand
Polysaccharides from Lycium barbarum ameliorate amyloid pathology and cognitive functions in APP/PS1 transgenic mice.
  • Yue Zhou, Y. Duan, +9 authors G. Pei
  • Biology, Medicine
  • International journal of biological macromolecules
  • 2019
Benzo(a)pyrene exposure induced neuronal loss, plaque deposition, and cognitive decline in APP/PS1 mice
Therapeutic potential of naringin in neurological disorders.
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