Naringenin glucuronidation in liver and intestine microsomes of humans, monkeys, rats, and mice.

Abstract

Naringenin, a flavanone found in citrus fruits, is mainly metabolized into glucuronide(s) by UDP-glucuronosyltransferase (UGT) enzymes in mammals. In the present study, the glucuronidation of naringenin in the liver and intestine microsomes of humans, monkeys, rats, and mice was examined. The kinetics of 7-glucuronidation in human liver and intestine… (More)
DOI: 10.1016/j.fct.2017.11.057

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