Naringenin and 17β‐estradiol coadministration prevents hormone‐induced human cancer cell growth

  title={Naringenin and 17β‐estradiol coadministration prevents hormone‐induced human cancer cell growth},
  author={P. Bulzomi and A. Bolli and P. Galluzzo and S. Leone and F. Acconcia and M. Marino},
  journal={IUBMB Life},
  • P. Bulzomi, A. Bolli, +3 authors M. Marino
  • Published 2010
  • Biology, Medicine
  • IUBMB Life
  • Flavonoids have been described as health‐promoting, disease‐preventing dietary components. In vivo and in vitro experiments also support a protective effect of flavonoids to reduce the incidence of certain hormone‐responsive cancers. In particular, our previous results indicate that the flavanone naringenin (Nar), decoupling estrogen receptor α (ERα) action mechanisms, drives cancer cells to apoptosis. Because these studies were conducted in the absence of the endogenous hormone 17β‐estradiol… CONTINUE READING
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