Naringenin and 17β‐estradiol coadministration prevents hormone‐induced human cancer cell growth
@article{Bulzomi2010NaringeninA1, title={Naringenin and 17β‐estradiol coadministration prevents hormone‐induced human cancer cell growth}, author={P. Bulzomi and A. Bolli and P. Galluzzo and S. Leone and F. Acconcia and M. Marino}, journal={IUBMB Life}, year={2010}, volume={62} }
Flavonoids have been described as health‐promoting, disease‐preventing dietary components. In vivo and in vitro experiments also support a protective effect of flavonoids to reduce the incidence of certain hormone‐responsive cancers. In particular, our previous results indicate that the flavanone naringenin (Nar), decoupling estrogen receptor α (ERα) action mechanisms, drives cancer cells to apoptosis. Because these studies were conducted in the absence of the endogenous hormone 17β‐estradiol… CONTINUE READING
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