Naringenin and 17β‐estradiol coadministration prevents hormone‐induced human cancer cell growth

@article{Bulzomi2010NaringeninA1,
  title={Naringenin and 17β‐estradiol coadministration prevents hormone‐induced human cancer cell growth},
  author={P. Bulzomi and A. Bolli and P. Galluzzo and S. Leone and F. Acconcia and M. Marino},
  journal={IUBMB Life},
  year={2010},
  volume={62}
}
  • P. Bulzomi, A. Bolli, +3 authors M. Marino
  • Published 2010
  • Biology, Medicine
  • IUBMB Life
    • Flavonoids have been described as health‐promoting, disease‐preventing dietary components. In vivo and in vitro experiments also support a protective effect of flavonoids to reduce the incidence of certain hormone‐responsive cancers. In particular, our previous results indicate that the flavanone naringenin (Nar), decoupling estrogen receptor α (ERα) action mechanisms, drives cancer cells to apoptosis. Because these studies were conducted in the absence of the endogenous hormone 17β‐estradiol… CONTINUE READING
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    39 Citations
    Background Citations
    18
    Methods Citations
    1
    Results Citations
    1
    39 Citations
    Citation Type

    Citation Type

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    Susceptibility of estrogen receptor rapid responses to xenoestrogens: Physiological outcomes
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    A naringenin-tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells.
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    Beyond the Antioxidant Activity of Dietary Polyphenols in Cancer: the Modulation of Estrogen Receptors (ERs) Signaling
    • 20
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    Xenoestrogen regulation of ERα/ERβ balance in hormone-associated cancers
    • 29
    Inhibition of the MAPK pathway alone is insufficient to account for all of the cytotoxic effects of naringenin in MCF-7 breast cancer cells
    • 9
    Targeting inflammatory pathways by flavonoids for prevention and treatment of cancer.
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