Narcotic abstinence in dependent rats: EEG and behavioral correlates

@article{Young1980NarcoticAI,
  title={Narcotic abstinence in dependent rats: EEG and behavioral correlates},
  author={G. Young and G. F. Steinfels and N. Khazan},
  journal={Pharmacology Biochemistry and Behavior},
  year={1980},
  volume={13},
  pages={115-119}
}
  • G. Young, G. F. Steinfels, N. Khazan
  • Published 1980
  • Psychology, Medicine
  • Pharmacology Biochemistry and Behavior
  • The purpose of the study was to assess and compare EEG and behavioral correlates of abstinence from morphine, methadone, LAAM, NLAAM, and DNLAAM in dependent rats. Rats were initially trained to lever press for self-injections on a FR-20 schedule of reinforcement. Following substitution of saline for each of the narcotic agonists. REM sleep was significantly suppressed during morphine, methadone, and NLAAM abstinence, but not during LAAM and DNLAAM abstinence. Significant increases in lever… CONTINUE READING
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