Narcolepsy-cataplexy in Israeli Jews is associated exclusively with the HLA DR2 haplotype. A study at the serological and genomic level.

@article{Wilner1988NarcolepsycataplexyII,
  title={Narcolepsy-cataplexy in Israeli Jews is associated exclusively with the HLA DR2 haplotype. A study at the serological and genomic level.},
  author={A Wilner and Lawrence Steinman and Peretz Lavie and Ron Peled and Adam Friedmann and Chaim Brautbar},
  journal={Human immunology},
  year={1988},
  volume={21 1},
  pages={15-22}
}
Narcolepsy is a very rare disease among Israeli Jews with a frequency of 7/3 X 10(6). An investigation of the association of narcolepsy with the human leukocyte antigen system was conducted in Israeli Jews at the serologic and genomic levels. The human leukocyte antigen class I and class II antigen typing of 7 clinically diagnosed narcoleptics, 3 individuals suffering from sleep disorders other than narcolepsy, and 11 healthy matched controls revealed that all narcoleptic patients (100… CONTINUE READING

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